Myopalladin (MYPN) and titin (TTN) play key roles in skeletal muscle structural organization and for thos reason they may be functional candidates fo meat production traits in pigs. We analyzed by PCR-RFLP two polymorphisms previously identified and described in the 3'UTR of MYPN and TTN genes in a group of Italian Large White (ILW) and Italian Duroc (ID) pigs with extreme divergent breeding values for some production traits. Signifcant allele frequency differences were observed for lean cuts (LC) at the MYPN locus in ILW breed and for Visible Intermuscolar Fat (VIF) at MYPN and TTN loci in ID breed. Moreover, association analysis between the two genes and some production traits (Average Daily Gain, LC, Backfat Thickness, Ham Weight, Feed Conversion Ratio, and VPF) was performed in a sample of 409 ILW and 381 ID pigs. On the whole, the results showed significant effects of both genes on some of the considered traits in the ID breed, and for TTN genes in ILW animals. These results indicate that both genes can be considerd as candidates for meat and carcass traits in ID pigs.
|Autori:||Braglia, S.;Davoli, R.;Zappavigna, A.;Zambonelli, P.;Buttazzoni, L.;Gallo, M.;Russo V.|
|Data di pubblicazione:||2013|
|Titolo:||SNPs of MYPN and TTN genes are associated to meat and carcass traits in Italian Large-White and Italian Duroc pigs|
|Rivista:||MOLECULAR BIOLOGY REPORTS|
|Appare nelle tipologie:||1.1 Articolo in rivista|