Apart from large amounts of cannabidiol, the known stilbenoids 1e4 and the oxylipins 7 and 8, a fibre cultivar of Cannabis sativa derived from the historical Carmagnola variety gave the novel spiranic stilbenoid isocannabispiradienone (5) and the biphenyl-type cannabinoid cannabioxepane (CBX, 6), a tetracyclic compound characterized by an unprecedented C-5/C-80 oxygen bridge and devoid of cannabinoid activity. Structures were established by analysis of MS and NMR data, and the biogenetic derivation of the new compounds is discussed.
|Autori:||Pagani, A.;Scala, F.;Chianese, G.;Grassi, G.;Appendino, G.;Taglialatela-Scafati, O.|
|Data di pubblicazione:||2011|
|Titolo:||Cannabioxepane, a novel tetracyclic cannabinoid from hemp, Cannabis sativa L.|
|Appare nelle tipologie:||1.1 Articolo in rivista|