We examined whether physical activity (PA) influences the association between birth weight and serum leptin in adolescents. The study comprised a total of 538 adolescents (315 girls), aged 12.5–17.49 years, born at term (≥37 weeks of gestation). We measured serum leptin levels and time engaged in moderate-vigorous PA (MVPA) by accelerometry. There was an interaction effect between birth weight and meeting the PA recommendations (60 min/day MVPA) on leptin levels in girls (P = 0.023) but not in boys (P = 0.809). Birth weight was negatively associated with leptin levels in girls not meeting the PA recommendations (i.e. more than 60 min/day of MVPA) (β = −0.096, P = 0.009), whereas no significant association was observed in those meeting the PA recommendations (β = −0.061, P = 0.433). In conclusion, meeting the PA recommendations may attenuate the negative effect of low birth weight on serum leptin levels in European female adolescents.
|Autori:||Labayena, I.;Ortega, F.B.;Moreno, L.A.;Gonzalez-Gross, M.;Jimenez-Pavon, D.;Martínez-Gómez, D.;Breidenasse, C.;Marcos, A.;Molnari, D.;Manios, Y.;Pladak, M.;Kafatosk, A.;De Henauw, S.;Mauro, B.;Zaccaria, M.;Widhalm, K.;Gottrando, F.;Castillo, M.J.;Sjöström, M.;Ruiz, J.R. on behalf of the Helena study group|
|Data di pubblicazione:||2013|
|Titolo:||Physical activity attenuates the negative effect of low birth weight on leptin levels in European adolescents; The HELENA study|
|Rivista:||NMCD. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES|
|Appare nelle tipologie:||1.1 Articolo in rivista|